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- Title
Central retinal vein and cilioretinal artery occlusion in a case of systemic sclerosis treated with a JAK inhibitor figlotinib.
- Authors
Jevnikar, Kristina; Mekjavić, Polona Jaki; Valentinčič, Nataša Vidovič; Ambrožič, Aleš; Hočevar, Alojzija
- Abstract
The article discusses the case of a patient with systemic sclerosis treated with the Janus kinase inhibitor (JAKi) filgotinib who developed central retinal vein and cilioretinary artery occlusion in the eye. Topics discussed include visual loss suffered by the patient, the thrombotic and cardiovascular adverse effects of JAKi, and the European Medicines Agency's guidance with the use of JAKi in older patients and patients with risk of cardiovascular events and malignancies.
- Subjects
VASCULAR endothelial growth factors; VISION disorders; OPTICAL coherence tomography; INTRAVITREAL injections; JANUS kinases; RETINAL vein occlusion; RETINAL artery occlusion; SYSTEMIC scleroderma; NEUROTRANSMITTER uptake inhibitors
- Publication
Rheumatology, 2024, Vol 63, Issue 9, pe273
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/keae206