We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Nickel‐Catalyzed Asymmetric Reductive Diarylation of Vinylarenes.
- Authors
Anthony, David; Lin, Qiao; Baudet, Judith; Diao, Tianning
- Abstract
A nickel‐catalyzed asymmetric diarylation reaction of vinylarenes enables the preparation of chiral α,α,β‐triarylated ethane scaffolds, which exist in a number of biologically active molecules. The use of reducing conditions with aryl bromides as coupling partners obviates the need for stoichiometric organometallic reagents and tolerates a broad range of functional groups. The application of an N‐oxyl radical as a ligand to a nickel catalyst represents a novel approach to facilitate nickel‐catalyzed cross‐coupling reactions.
- Subjects
ENANTIOSELECTIVE catalysis; ALKENES; RING formation (Chemistry); CATALYSTS; CATALYSIS
- Publication
Angewandte Chemie, 2019, Vol 131, Issue 10, p3230
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201900228