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- Title
Molecular phylogeny of modern coxsackievirus A16.
- Authors
Perera, D.; Yusof, M. A.; Podin, Y.; Ooi, M. H.; Thao, N. T. T.; Wong, K. K.; Zaki, A.; Chua, K. B.; Malik, Y. A.; Tu, P. V.; Tien, N. T. K.; Puthavathana, P.; McMinn, P. C.; Cardosa, M. J.
- Abstract
A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7–30.2% and 19.9–25.2% in VP1 and VP4, respectively, in relation to other CVA16 strains, which formed two separate lineages in genogroup B with nucleotide variation of less than 13.4% and less than 16.3% in VP1 and VP4, respectively. Lineage 1 strains circulating before 2000 were later displaced by lineage 2 strains.
- Subjects
PHYLOGENY; NUCLEOTIDES; COXSACKIEVIRUSES; ENTEROVIRUSES; NUCLEOTIDE sequence
- Publication
Archives of Virology, 2007, Vol 152, Issue 6, p1201
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-006-0934-5