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- Title
First Case of F-FACBC PET/CT-Guided Salvage Retroperitoneal Lymph Node Dissection for Disease Relapse after Radical Prostatectomy for Prostate Cancer and Negative <sup>11</sup>C-Choline PET/CT: New Imaging Techniques May Expand Pioneering Approaches.
- Authors
Schiavina, Riccardo; Concetti, Sergio; Brunocilla, Eugenio; Nanni, Cristina; Borghesi, Marco; Gentile, Giorgio; Cevenini, Matteo; Bianchi, Lorenzo; Molinaroli, Enrico; Fanti, Stefano; Martorana, Giuseppe
- Abstract
We present the first case of salvage retroperitoneal lymph node dissection based on the results of 18F-FACBC PET/CT performed for a prostate-specific antigen relapse after radical prostatectomy. The patients underwent 11C-choline PET/CT, which turned out negative, while 18F-FACBC PET/CT visualized two lymph node metastases confirmed at pathological examination. Preliminary clinical reports showed an improvement in the detection rate of 20-40% for 18F-FACBC in comparison with 11C-choline, rendering the 18F-FACBC the potential radiotracer of the future. Salvage surgery for prostate cancer is a fascinating but controversial approach. New diagnostic tools may improve its potential by increasing the assessment and the selection of the patients. © 2013 S. Karger AG, Basel
- Subjects
RETROPERITONEAL fibrosis; LYMPH node surgery; DISEASE relapse; PROSTATECTOMY; DIAGNOSIS; PROSTATE cancer; ANTIGENS
- Publication
Urologia Internationalis, 2014, Vol 92, Issue 2, p242
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000354730