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- Title
Ugi Reaction of Amino Acids: From Facile Synthesis of Polypeptoids to Sequence‐Defined Macromolecules.
- Authors
Tao, Yue; Tao, Youhua
- Abstract
Polypeptoids have been prepared and researched for more than 20 years. However, the efficient generation of polypeptoids and sequence‐defined polypeptoids faces many challenges and difficulties. The Ugi reaction of amino acids has recently been introduced into polypeptoid chemistry as a new and powerful method to furnish polypeptoids. In the following mini review, the recent progress on the application of the Ugi reaction of amino acids in polypeptoid science, including polypeptoid from sustainable furfural, sequence‐defined polypeptoids, and more is summarized. Moreover, the future development of the Ugi reaction of amino acids in polypeptoid science is discussed.
- Subjects
AMINO acids; MACROMOLECULES; FURFURAL
- Publication
Macromolecular Rapid Communications, 2021, Vol 42, Issue 6, p1
- ISSN
1022-1336
- Publication type
Article
- DOI
10.1002/marc.202000515