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- Title
Elimination of cefuroxime and gentamicin during and after open heart surgery.
- Authors
Lippert, Søren; Josephsen, Susanne D.; Jendresen, Marianne; Sørensen, Torben Sandberg; Gutschik, Ernö; Lippert, S; Josephsen, S D; Jendresen, M; Sørensen, T S; Gutschik, E
- Abstract
In eight consecutive adult heart surgery patients, serum concentrations of cefuroxime and gentamicin were studied during and after operation. Repeated doses of cefuroxime 1·5 g and gentamicin 80 mg were given. Intra-operative concentrations were deemed adequate (cefuroxime : 16–45 mg/l, gentamicin C: 1·6–2·8 mg/l), and no differences ( = 0·05) could be demonstrated between elimination rates during and after open heart operation (cefuroxime 101 vs 111 min, gentamicin 191 vs 193 min).
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1989, Vol 24, Issue 5, p775
- ISSN
0305-7453
- Publication type
journal article