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Il-10 signaling reduces survival in mouse models of synucleinopathy.
Published in:
NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00169-8
By:
- Cockey, Samuel G.;
- McFarland, Karen N.;
- Koller, Emily J.;
- Brooks, Mieu M. T.;
- Gonzalez De La Cruz, Elsa;
- Cruz, Pedro E.;
- Ceballos-Diaz, Carolina;
- Rosario, Awilda M.;
- Levites, Yona R.;
- Borchelt, David R.;
- Golde, Todd E.;
- Giasson, Benoit I.;
- Chakrabarty, Paramita
Publication type:
Article
Fyn depletion ameliorates tauP301L-induced neuropathology.
Published in:
Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00979-6
By:
- Liu, Guanghao;
- Fiock, Kimberly L.;
- Levites, Yona;
- Golde, Todd E.;
- Hefti, Marco M.;
- Lee, Gloria
Publication type:
Article
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09825-2
By:
- Heath, Laura;
- Earls, John C.;
- Magis, Andrew T.;
- Kornilov, Sergey A.;
- Lovejoy, Jennifer C.;
- Funk, Cory C.;
- Rappaport, Noa;
- Logsdon, Benjamin A.;
- Mangravite, Lara M.;
- Kunkle, Brian W.;
- Martin, Eden R.;
- Naj, Adam C.;
- Ertekin-Taner, Nilüfer;
- Golde, Todd E.;
- Hood, Leroy;
- Price, Nathan D.;
- Alzheimer's Disease Genetics Consortium;
- Abner, Erin;
- Adams, Perrie M.;
- Albert, Marilyn S.
Publication type:
Article
AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model.
Published in:
EMBO Molecular Medicine, 2022, v. 14, n. 4, p. 1, doi. 10.15252/emmm.201809824
By:
- Marino, Marika;
- Zhou, Lujia;
- Rincon, Melvin Y;
- Callaerts‐Vegh, Zsuzsanna;
- Verhaert, Jens;
- Wahis, Jérôme;
- Creemers, Eline;
- Yshii, Lidia;
- Wierda, Keimpe;
- Saito, Takashi;
- Marneffe, Catherine;
- Voytyuk, Iryna;
- Wouters, Yessica;
- Dewilde, Maarten;
- Duqué, Sandra I;
- Vincke, Cécile;
- Levites, Yona;
- Golde, Todd E;
- Saido, Takaomi C;
- Muyldermans, Serge
Publication type:
Article
High‐affinity interactions and signal transduction between Aβ oligomers and TREM2.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 11, p. N.PAG, doi. 10.15252/emmm.201809027
By:
- Lessard, Christian B;
- Malnik, Samuel L;
- Zhou, Yingyue;
- Ladd, Thomas B;
- Cruz, Pedro E;
- Ran, Yong;
- Mahan, Thomas E;
- Chakrabaty, Paramita;
- Holtzman, David M;
- Ulrich, Jason D;
- Colonna, Marco;
- Golde, Todd E
Publication type:
Article
γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 7, p. 950, doi. 10.15252/emmm.201607265
By:
- Ran, Yong;
- Hossain, Fokhrul;
- Pannuti, Antonio;
- Lessard, Christian B;
- Ladd, Gabriela Z;
- Jung, Joo In;
- Minter, Lisa M;
- Osborne, Barbara A;
- Miele, Lucio;
- Golde, Todd E
Publication type:
Article
β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.
Published in:
EMBO Molecular Medicine, 2012, v. 4, n. 9, p. 980, doi. 10.1002/emmm.201101084
By:
- Cai, Jun;
- Qi, Xiaoping;
- Kociok, Norbert;
- Skosyrski, Sergej;
- Emilio, Alonso;
- Ruan, Qing;
- Han, Song;
- Liu, Li;
- Chen, Zhijuan;
- Bowes Rickman, Catherine;
- Golde, Todd;
- Grant, Maria B.;
- Saftig, Paul;
- Serneels, Lutgarde;
- de Strooper, Bart;
- Joussen, Antonia M.;
- Boulton, Michael E.
Publication type:
Article
Inflammation takes on Alzheimer disease.
Published in:
Nature Medicine, 2002, v. 8, n. 9, p. 936, doi. 10.1038/nm0902-936
By:
- Golde, Todd E.
Publication type:
Article
Amyloid-β Immunization Effectively Reduces Amyloid Deposition in FcRγ[sup-/-] Knock-Out Mice.
Published in:
Journal of Neuroscience, 2003, v. 23, n. 24, p. 8532, doi. 10.1523/JNEUROSCI.23-24-08532.2003
By:
- Das, Pritam;
- Howard, Victor;
- Loosbrock, Nicole;
- Dickson, Dennis;
- Murphy, M. Paul;
- Golde, Todd E.
Publication type:
Article
Notch1 augments NF-κB activity by facilitating its nuclear retention.
Published in:
EMBO Journal, 2006, v. 25, n. 1, p. 129, doi. 10.1038/sj.emboj.7600902
By:
- Hyun Mu Shin;
- Minter, Lisa M.;
- Ok HyunCho;
- Gottipati, Sridevi;
- Fauq, Abdul H.;
- Golde, Todd E.;
- Sonenshein, Gail E.;
- Osborne, Barbara A.
Publication type:
Article
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4043, doi. 10.1002/alz.13821
By:
- Wojtas, Aleksandra M.;
- Dammer, Eric B.;
- Guo, Qi;
- Ping, Lingyan;
- Shantaraman, Ananth;
- Duong, Duc M.;
- Yin, Luming;
- Fox, Edward J.;
- Seifar, Fatemeh;
- Lee, Edward B.;
- Johnson, Erik C. B.;
- Lah, James J.;
- Levey, Allan I.;
- Levites, Yona;
- Rangaraju, Srikant;
- Golde, Todd E.;
- Seyfried, Nicholas T.
Publication type:
Article
Immune modulatory therapeutics in AD ‐ can we find the Goldilocks zone?
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.072029
By:
- Golde, Todd E
Publication type:
Article
Uncovering Novel Modifiers of Tau Aggregation and Pathology using a Proximity Proteomics Approach (BioID).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079920
By:
- Lee, Jannifer H;
- Morderer, Dmytro;
- Khalil, Bilal;
- Smith, Courtney L;
- Wren, Melissa C;
- Tsai, Chih‐Wei;
- Liu, Feilin;
- Croft, Cara L;
- Carlomagno, Yari;
- DeTure, Michael;
- Dickson, Dennis W.;
- Cook, Casey N.;
- Golde, Todd E;
- Petrucelli, Leonard;
- Rossoll, Wilfried
Publication type:
Article
Evaluating dynamic autophagic responses to tau inclusions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074246
By:
- Vontobel, Davi;
- Rowe, Lyla A;
- Goodwin, Marshall S;
- Ryu, Daniel H;
- McHutchon, Andrew;
- Golde, Todd E;
- Croft, Cara L
Publication type:
Article
Integrative omics studies to discover genetic determinants of brain cell type proportions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080786
By:
- Reddy, Joseph S.;
- Allen, Mariet;
- Patel, Tulsi;
- Quicksall, Zachary;
- Wang, Xue;
- Carnwath, Troy;
- Min, Yuhao;
- Golde, Todd E;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Network‐based pipeline guides knowledge‐driven prioritization and validation of therapeutic target discovery for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073832
By:
- Min, Yuhao;
- Wang, Xue;
- Gao, Junli;
- Zhang, Cheng;
- Ung, Choong;
- Chalk, Jessica L;
- Correia, Cristina;
- Golde, Todd E;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Zhang, Ke;
- Allen, Mariet;
- Li, Hu;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Integrative omics studies to discover genetic determinants of brain cell type proportions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080786
By:
- Reddy, Joseph S.;
- Allen, Mariet;
- Patel, Tulsi;
- Quicksall, Zachary;
- Wang, Xue;
- Carnwath, Troy;
- Min, Yuhao;
- Golde, Todd E;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Network‐based pipeline guides knowledge‐driven prioritization and validation of therapeutic target discovery for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073832
By:
- Min, Yuhao;
- Wang, Xue;
- Gao, Junli;
- Zhang, Cheng;
- Ung, Choong;
- Chalk, Jessica L;
- Correia, Cristina;
- Golde, Todd E;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Zhang, Ke;
- Allen, Mariet;
- Li, Hu;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Chimeric Phagocytic Receptors (CPR) to target Alzheimer's disease pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.068704
By:
- Levites, Yona;
- Ran, Yong;
- Erquizi, Aya;
- Iturbe, Andrea;
- Dillon, Kristy;
- Ryu, Danny;
- Moore, Brenda D;
- Golde, Todd E
Publication type:
Article
Investigating the functional significance of presynaptic tau in ageing and disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065852
By:
- Groves, Emily E;
- Sung, Katherine;
- Flores‐Dominguez, Diana;
- Pollack, Saskia J;
- Croft, Cara L;
- Golde, Todd E;
- Hanger, Diane P;
- McAdam, Robyn;
- Giese, Karl Peter;
- Noble, Wendy
Publication type:
Article
Identification of Novel Modifiers of Tau Aggregation and Pathology using a Proximity Proteomics Approach.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065671
By:
- Lee, Jannifer H;
- Morderer, Dmytro;
- Khalil, Bilal;
- Liu, Feilin;
- Tsai, Chih‐Wei;
- Croft, Cara L;
- Carlomagno, Yari;
- DeTure, Michael;
- Salemi, Michelle;
- Cook, Casey;
- Phinney, Brett;
- Dickson, Dennis W.;
- Golde, Todd E;
- Petrucelli, Leonard;
- Rossoll, Wilfried
Publication type:
Article
Targeting aggregated tau turnover as a therapeutic strategy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056366
By:
- Croft, Cara L;
- Goodwin, Marshall S;
- Ryu, Daniel H;
- Lessard, Christian B;
- Tejeda, Giancarlo;
- Marrero, Marc;
- Vause, Ava;
- Paterno, Giavanna;
- Cruz, Pedro E;
- Lewis, Jada;
- Giasson, Benoit;
- Golde, Todd E
Publication type:
Article
Conserved architecture of brain transcriptome changes between Alzheimer's disease and progressive supranuclear palsy in pathologically affected and unaffected regions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054424
By:
- Wang, Xue;
- Allen, Mariet;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Asmann, Yan W.;
- Funk, Cory C;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Younkin, Steven G.;
- Dickson, Dennis W;
- Price, Nathan D;
- Golde, Todd E;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 6, p. 984, doi. 10.1002/alz.12254
By:
- Li, Hong‐Dong;
- Funk, Cory C.;
- McFarland, Karen;
- Dammer, Eric B.;
- Allen, Mariet;
- Carrasquillo, Minerva M.;
- Levites, Yona;
- Chakrabarty, Paramita;
- Burgess, Jeremy D.;
- Wang, Xue;
- Dickson, Dennis;
- Seyfried, Nicholas T.;
- Duong, Duc M.;
- Lah, James J.;
- Younkin, Steven G.;
- Levey, Allan I.;
- Omenn, Gilbert S.;
- Ertekin‐Taner, Nilüfer;
- Golde, Todd E.;
- Price, Nathan D.
Publication type:
Article
Elucidating the relationship between TGF‐β signaling and Alzheimer's disease: Molecular and cell biology: Importance of Abeta/amyloid in brain changes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043570
By:
- Croft, Cara L.;
- Liu, Xuefei;
- Ryu, Daniel H.;
- Ceballos‐Diaz, Carolina;
- Tejeda, Giancarlo;
- Marrero, Marc;
- Moran, Corey;
- Cruz, Pedro E.;
- Ladd, Thomas;
- Moore, Brenda D.;
- Golde, Todd E.
Publication type:
Article
Using seeding models to understand strain differences from Alzheimer's disease and pathological aging brains: Development of new models and analysis methods/seeding and spreading of proteinopathies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043302
By:
- Moore, Brenda D.;
- Hampton, Hailey;
- Croft, Cara L.;
- Futch, Hunter S.;
- Moran, Corey;
- Levites, Yona;
- Fromholt, Susan;
- Xu, Guilian;
- Dickson, Dennis W.;
- Lewis, Jada;
- Golde, Todd E.;
- Borchelt, David R.
Publication type:
Article
Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 1095, doi. 10.1002/alz.12059
By:
- Knopman, David;
- Lemere, Cynthia A.;
- Lamb, Bruce T.;
- Craft, Suzanne;
- Gitlin, Laura N.;
- Golde, Todd E.;
- Pericak‐Vance, Margaret;
- Sano, Mary;
- Schellenberg, Gerard;
- Schneider, Julie A.;
- Zheng, Hui;
- Khachaturian, Zaven;
- Snyder, Heather M.;
- Carrillo, Maria C.
Publication type:
Article
P4‐614: PERCENTAGE OF INTRUSION ERRORS ON THE LASSI‐L COGNITIVE STRESS TEST DISCRIMINATES BETWEEN AMYLOID POSITIVE AND AMYLOID NEGATIVE INDIVIDUALS WITH AMNESTIC MILD COGNITIVE IMPAIRMENT AND EARLY DEMENTIA.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1560, doi. 10.1016/j.jalz.2019.08.162
By:
- Grau, Gabriella Amy;
- Garcia, Jessica;
- Leal, Giselle;
- Kitaigorodsky, Marcela;
- Curiel, Rosie E.;
- Duara, Ranjan;
- Greig-Custo, Maria T.;
- Golde, Todd E.;
- DeKosky, Steven T.;
- Loewenstein, David A.
Publication type:
Article
P4‐613: SEMANTIC INTRUSION ERRORS DIFFERENTIATE AMYLOID POSITIVE AMNESTIC MILD COGNITIVE IMPAIRMENT FROM COGNITIVELY HEALTHY CONTROLS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1560, doi. 10.1016/j.jalz.2019.08.161
By:
- Garcia, Jessica;
- Grau, Gabriella Amy;
- Leal, Giselle;
- Kitaigorodsky, Marcela;
- Curiel, Rosie E.;
- Duara, Ranjan;
- Greig-Custo, Maria T.;
- Golde, Todd E.;
- DeKosky, Steven T.;
- Loewenstein, David A.
Publication type:
Article
P4‐157: ROLE OF FYN IN A MOUSE MODEL OF TAU P301L TAUOPATHY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1334, doi. 10.1016/j.jalz.2019.06.3819
By:
- Liu, Guanghao;
- Levites, Yona;
- Golde, Todd E.;
- Lee, Gloria
Publication type:
Article
P4‐103: CELL‐TYPE SPECIFIC MECHANISTIC AND DIRECTIONAL TRANSCRIPTIONAL REGULATORY NETWORKS IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1314, doi. 10.1016/j.jalz.2019.06.3764
By:
- Funk, Cory C.;
- Shannon, Paul;
- Gibbs, David;
- Rappaport, Noa;
- Allen, Mariet;
- Carrasquillo, Minerva M.;
- Ertekin-Taner, Nilufer;
- Golde, Todd E.;
- Shmulevich, Ilya;
- Hood, Leroy;
- Price, Nathan D.
Publication type:
Article
P2‐427: THE RELATIONSHIP BETWEEN HISPANIC ETHNICITY, AMYLOID LOAD AND APOE4 CARRIER STATUS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P775, doi. 10.1016/j.jalz.2019.06.2834
By:
- Duara, Ranjan;
- Loewenstein, David A.;
- Lizarraga, Gabriel;
- Adjouadi, Malek;
- Barker, Warren W.;
- Greig-Custo, Maria T.;
- Rosselli, Monica;
- Curiel, Rosie E.;
- Hanson, Kevin;
- Marsiske, Michael;
- Ertekin-Taner, Nilufer;
- Vaillancourt, David;
- DeKosky, Steve;
- de Santi, Susan;
- Golde, Todd E.
Publication type:
Article
P3‐378: EFFECT OF AGE, GENDER, ETHNICITY, COGNITION AND APOE GENOTYPE ON AMYLOID LOAD AMONG NORMAL, MCI AND MILD DEMENTIA SUBJECTS USING [F‐18] FLORBETABEN.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1237, doi. 10.1016/j.jalz.2018.06.1740
By:
- Duara, Ranjan;
- Loewenstein, David A.;
- Lizarraga, Gabriel;
- Adjouadi, Malek;
- Barker, Warren W.;
- Greig-Custo, Maria T.;
- Penate, Ailyn;
- Hanson, Kevin;
- Marsiske, Michael;
- Burke, Shanna L.;
- Ertekin-Taner, Nilufer;
- Vaillancourt, David;
- DeKosky, Steve;
- de Santi, Susan;
- Golde, Todd E.
Publication type:
Article
P3‐091: MODELING TAUOPATHY USING AAV‐MEDIATED SOMATIC BRAIN TRANSGENESIS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1100, doi. 10.1016/j.jalz.2018.06.1447
By:
- Koller, Emily J.;
- De La Cruz, Elsa Gonzalez;
- Gaines, Katherine D.;
- Machula, Timothy A.;
- Strang, Kevin H.;
- Liu, Xuefei;
- Riffe, Cara J.;
- Ryu, Daniel;
- Janus, Christopher;
- Golde, Todd E.;
- Giasson, Benoit I.;
- Chakrabarty, Paramita
Publication type:
Article
O3‐03‐01: MECHANISTIC AND DIRECTIONAL TRANSCRIPTIONAL REGULATORY NETWORKS IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1014, doi. 10.1016/j.jalz.2018.06.2782
By:
- Funk, Cory C.;
- Richards, Matthew A.;
- Shannon, Paul;
- Donovan-Maiye, Rory;
- Rappaport, Noa;
- Robinson, Max;
- Allen, Mariet;
- Carrasquillo, Minerva M.;
- Chakrabarty, Paramita;
- McFarland, Karen;
- Jung, Segun C.;
- Rodriguez, Alex;
- Ertekin-Taner, Nilufer;
- Golde, Todd E.;
- Hood, Leroy;
- Foster, Ian;
- Ament, Seth;
- Madduri, Ravi;
- Price, Nathan D.
Publication type:
Article
P2‐063: A NOVEL IMMUNOTHERAPEUTIC APPROACH TO SIMULTANEOUSLY TARGET BEHAVIORAL STRESS AND DOWNSTREAM PATHOLOGIES IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P690, doi. 10.1016/j.jalz.2018.06.748
By:
- Futch, Hunter S.;
- Kuhn, Mike Zino;
- Levites, Yona;
- Moore, Brenda D.;
- Janus, Christopher;
- Golde, Todd E.
Publication type:
Article
P1‐177: OVEREXPRESSION OF APP INTRACELLULAR DOMAIN RESCUES MEMORY IN ALZHEIMER'S DISEASE MOUSE MODELS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P346, doi. 10.1016/j.jalz.2018.06.181
By:
- Deyts, Carole;
- Clutter, Mary;
- Pierce, Nicholas;
- Cruz, Pedro E.;
- Golde, Todd E.;
- Parent, Angèle
Publication type:
Article
Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer's Disease Like Amyloid Pathology in APP-TgCRND8 Mice.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3328, doi. 10.3390/ijms23063328
By:
- Aravindraja, Chairmandurai;
- Sakthivel, Ravi;
- Liu, Xuefei;
- Goodwin, Marshall;
- Veena, Patnam;
- Godovikova, Valentina;
- Fenno, J. Christopher;
- Levites, Yona;
- Golde, Todd E.;
- Kesavalu, Lakshmyya
Publication type:
Article
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 10, p. 4158, doi. 10.1172/JCI69003
By:
- Blair, Laura J.;
- Nordhues, Bryce A.;
- Hill, Shannon E.;
- Scaglione, K. Matthew;
- O'Leary III, John C.;
- Fontaine, Sarah N.;
- Breydo, Leonid;
- Bo Zhang;
- Pengfei Li;
- Li Wang;
- Cotman, Carl;
- Paulson, Henry L.;
- Muschol, Martin;
- Uversky, Vladimir N.;
- Klengel, Torsten;
- Binder, Elisabeth B.;
- Kayed, Rakez;
- Golde, Todd E.;
- Berchtold, Nicole;
- Dickey, Chad A.
Publication type:
Article
Thinking laterally about neurodegenerative proteinopathies.
Published in:
2013
By:
- Golde, Todd E;
- Borchelt, David R;
- Giasson, Benoit I;
- Lewis, Jada
Publication type:
journal article
Thinking laterally about neurodegenerative proteinopathies.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 1847, doi. 10.1172/JCI66029
By:
- Golde, Todd E.;
- Borchelt, David R.;
- Giasson, Benoit I.;
- Lewis, Jada
Publication type:
Article
Dysfunction of TGF-β signaling in Alzheimer's disease.
Published in:
Journal of Clinical Investigation, 2006, v. 116, n. 11, p. 2855, doi. 10.1172/JCI30284
By:
- Das, Pritam;
- Golde, Todd
Publication type:
Article
Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model.
Published in:
2006
By:
- Levites, Yona;
- Das, Pritam;
- Price, Robert W.;
- Rochette, Marjorie J.;
- Kostura, Lisa A.;
- McGowan, Eileen M.;
- Murphy, Michael P.;
- Golde, Todd E.
Publication type:
journal article
Production of Amyloid β Protein from Normal Amyloid β-Protein Precursor (βAPP) and the Mutated βAPPS Linked to Familial Alzheimer's Disease.
Published in:
Annals of the New York Academy of Sciences, 1993, v. 695, n. 1, p. 103, doi. 10.1111/j.1749-6632.1993.tb23036.x
By:
- GOLDE, TODD E.;
- CAI, XIAO-DAN;
- SHOJI, MIKIO;
- YOUNKIN, STEVEN G.
Publication type:
Article
Normal Processing of the Alzheimer's Disease Amyloid β Protein Precursor Generates Potentially Amyloidogenic Carboxyl-Terminal Derivatives.
Published in:
Annals of the New York Academy of Sciences, 1992, v. 674, n. 1, p. 138, doi. 10.1111/j.1749-6632.1992.tb27483.x
By:
- ESTUS, STEVEN;
- GOLDE, TODD E.;
- YOUNKIN, STEVEN G.
Publication type:
Article
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03373-1
By:
- Xia, Yuxing;
- Prokop, Stefan;
- Bell, Brach M.;
- Gorion, Kimberly-Marie M.;
- Croft, Cara L.;
- Nasif, Lith;
- Xu, Guilian;
- Riffe, Cara J.;
- Manaois, Alyssa N.;
- Strang, Kevin H.;
- Quintin, Stephan S.;
- Paterno, Giavanna;
- Tansey, Malú Gámez;
- Borchelt, David R.;
- Golde, Todd E.;
- Giasson, Benoit I.
Publication type:
Article
Clinical utility of plasma Aβ42/40 ratio by LC-MS/MS in Alzheimer's disease assessment.
Published in:
Frontiers in Neurology, 2024, p. 01, doi. 10.3389/fneur.2024.1364658
By:
- Weber, Darren M.;
- Taylor, Steven W.;
- Lagier, Robert J.;
- Kim, Jueun C.;
- Goldman, Scott M.;
- Clarke, Nigel J.;
- Vaillancourt, David E.;
- Duara, Ranjan;
- McFarland, Karen N.;
- Wei-en Wang;
- Golde, Todd E.;
- Racke, Michael K.
Publication type:
Article
Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila.
Published in:
Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13195-020-00698-z
By:
- De Mena, Lorena;
- Smith, Michael A.;
- Martin, Jason;
- Dunton, Katie L.;
- Ceballos-Diaz, Carolina;
- Jansen-West, Karen R.;
- Cruz, Pedro E.;
- Dillon, Kristy D.;
- Rincon-Limas, Diego E.;
- Golde, Todd E.;
- Moore, Brenda D.;
- Levites, Yona
Publication type:
Article
γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not.
Published in:
Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00622-5
By:
- Lessard, Christian B.;
- Rodriguez, Edgardo;
- Ladd, Thomas B.;
- Minter, Lisa M.;
- Osborne, Barbara A.;
- Miele, Lucio;
- Golde, Todd E.;
- Ran, Yong
Publication type:
Article
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph.
Published in:
Alzheimer's Research & Therapy, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13195-019-0469-0
By:
- Magno, Lorenza;
- Lessard, Christian B.;
- Martins, Marta;
- Lang, Verena;
- Cruz, Pedro;
- Asi, Yasmine;
- Katan, Matilda;
- Bilsland, Jamie;
- Lashley, Tammaryn;
- Chakrabarty, Paramita;
- Golde, Todd E.;
- Whiting, Paul J.
Publication type:
Article

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