We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Advancements in Wound Care: A Review of Electrospun Nanofibrous Dressings Enriched with Phytoconstituents.
- Authors
Kota, Sobha; Dumpala, Pradeep; Sajja, Radhika; Anantha, Ratnakumari
- Abstract
The wound healing process is a revelation of the complexity of the human system, often challenged by pathogens that overpower even the best antibiotics and render treatment regimens ineffective. Further, persistent disorders like diabetes and critical conditions like in-depth wounds are potential hurdles in wound care management because of inadequate antibacterial, antioxidant, and anti-inflammatory properties of the current wound dressings. A few multifunctional wound dressings with tailored antibacterial, antioxidant, and anti-inflammatory properties are presented, emphasising the imperative need to improve them in order to reduce the high morbidity and mortality rates. A critical survey of the recent wound-care products indicated a limited use of phytochemicals like volatile oils, alkaloids, flavonoids, phenols, quinines, saponins, and glycosides. Bioactives, such as curcumin, baicalin, limonene/black pepper oil, Acacia extract, Momordica charantia pulp, Agrimonia eupatoria L. extract, surfactin, hesperidin, and metal nanoparticles, viz. zinc oxide, cerium oxide, titanium dioxide, silver, copper, and gold analogues, used in the fabrication of synthetic or hybrid polymeric dressings, are discussed. The need and rationale of the production of biological and/or chemical polymeric nano-fibrous composite-based "smart dressings" by electrospinning and the inclusion of phyto-constituents that delay the onset of infection and alleviate antibiotic drug resistance are highlighted.
- Subjects
WOUND care; PHYTOCHEMICALS; ESSENTIAL oils; METAL nanoparticles; COPPER; MOMORDICA charantia
- Publication
Annales de Chimie Science des Matériaux, 2024, Vol 48, Issue 2, p269
- ISSN
0151-9107
- Publication type
Article
- DOI
10.18280/acsm.480213