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- Title
限制性液体复苏对失血性休克复苏患者血浆TNF-α、IL-6水平的影响.
- Authors
杨嘉琳; 池凯仪; 龙振鸿; 徐文婷; 徐仲
- Abstract
Objective:To explore the effect of limited fluid resuscitation on plasma tumor necrosis factor-α(TNF-α ) and interleukin- 6(IL-6) levels in patients with hemorrhagic shock resuscitation, to provide the basis for clinical treatment of hemorrhagic shock in the choice of liquid recovery. Methods: Selected 63 cases of patients with hemorrhagic shock in our hospital from January 2010 to June 2015 as the research object; Which were divided into observation group(32 patients) and control group (31 patients) by random number table method, the patients in observation group was given a limited fluid resuscitation, and the patients in control group received traditional full recovery; Observed and compared the changes of plasma TNF-α and IL-6 levels in two groups before and after treatment. Results: The input of recovery fluid of the patients in the observation group was(1.95 + 0.35) L, which was significant higher than (3.61 + 0.56)L of control group, the difference was statistically significant(P<0.05); There was no significant difference in plasma TNF-α and IL-6 levels between the two groups before treatment(P>0.05); The plasma levels of TNF-α and IL-6 in the two groups were significantly in- creased, and plasma TNF-αand IL-6 levels in the observation group were significantly lower than those in the control group after treat- ment, the difference was statistically significant(P<0.05).Conclusion: Limited fluid resuscitation can significantly reduce the amount of bleeding in patients with hemorrhagic shock, stabilize the blood flow dynamics and ensure the blood flow of the important organs of the body; It is beneficial to improve the level of plasma IL-6 and TNF-α in patients,improve the therapeutic effect and improve prognosis.
- Publication
Progress in Modern Biomedicine, 2016, Vol 16, Issue 13, p2513
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2016.13.030