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- Title
中药防治假体周围骨溶解的研究进展.
- Authors
金亮; 孙闯; 于大淼; 徐英; 郑未来; 廉永云
- Abstract
Now arthroplasty more and more used in the reconstruction of joint function to improve the quality of life in patients with joint disease, but serious postoperative complications affecting the effect of the surgery, artificial periprosthetic osteolysis and aseptic loosening one of the main reasons for artificial joint replacement surgery failed, so how to prevent and how to go after the onset of treatment has become an important issue that the joint doctors face. OPG/RANKL/RANK system, inflammatory cytokine production, osteoclasts, and osteoblasts are affecting the prosthesis postoperative produce aseptic loosening, and raises an important factor in periprosthetic osteolysis, effective drug intervention treatment has become a hot topic now in joint replacement surgery and perioperative medicine because of its side effects, unique effect, and in-depth research gradually by the attention of the majority of doctors, Chinese medicine in the treatment of prosthesis loosening and osteolysis has also been a major breakthrough. From the Chinese kidney storing the essence, the essence bringing forth marrow, and the theory that marrow can raise bone, this review summarizes the research status of the traditional Chinese medicine acting on the OPG/RANKL/RANK system, inhibition of inflammatory factors, osteoclasts and promote bone cell proliferation research.
- Publication
Progress in Modern Biomedicine, 2015, Vol 15, Issue 7, p1380
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2015.07.048