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- Title
Bioaccessibility of micro and nanoencapsulated vegetable antioxidants: In vitro assessment perspectives.
- Authors
Hernández-Jabalera, Anaid; Mena-Martínez, María; León-Espinosa, Erika B.; Rayas-Amor, Adolfo A.; Díaz-Ramírez, Mayra; Jiménez-Guzmán, Judith; García-Garibay, Mariano; Miranda de la Lama, Genaro; Cruz-Monterrosa, Rosy G.
- Abstract
Objective: Identify and discuss the approaches commonly used to assess in vitro bioaccesibility of micro and nanoencapsulated vegetal antioxidants. The emphasis is on identifying the scope and limitations of the encapsulation techniques and the digestive models. Design/methodology/approach: Analytic discussion of scientific papers gather through SCOPUS, EBSCO, ScienceDirect, Pubmed and Google scholar databases by using the following keywords: Antioxidant, Vegetable, Micro/nanoencapsulation, Bioaccesibillity, In vitro digestion, Release. Results: A consistent trend identified is the privileged use of extracts over purified molecules, the use of by-products in systems produced by broad-distribution technologies. Among in vitro models, static models are generally preferred although there is a great variation in the components and digestive stages considered. The analysis of the accumulated experience provides encouraging evidence in terms of resistance to gastric conditions and greater release during the intestinal phase for a dispersible amount of micro or nanocapsules. Limitations on study/Implications: This review is limited in its scope due to the scarce information on promising systems that have not been tested in simulations of digestion. Those studies are not considered in the array of studies reviewed here. Findings/conclusions: In order to transition from reported experimental data to the real bioaccesibility of antioxidants from vegetal sources, standardization of in vitro digestive static systems need to be addressed. Additionally, the most urgent limitations to be overcome included initial loses during encapsulation, characterization of release type, punctual accumulation and toxic effects and comparison of achieved bioaccessible concentrations against concentrations needed for in vivo effect.
- Subjects
GOOGLE (Web resource); NANOCAPSULES; VEGETABLES; ANTIOXIDANTS; DIGESTIVE organs; INFORMATION storage &; retrieval systems; DIGESTION
- Publication
Agro Productividad, 2019, Vol 12, Issue 11, p29
- ISSN
2448-7546
- Publication type
Article
- DOI
10.32854/agrop.vi0.1500