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- Title
Note: Ectopic Overproduction of a Sporulation-Specific Transcription Factor Induces Assembly of Prespore-Like Membranous Compartments in Vegetative Cells of Fission Yeast.
- Authors
Nakase, Yukiko; Hirata, Aiko; Shimoda, Chikashi; Nakamura, Taro
- Abstract
Mei4 is a key sporulation-specific transcription factor in fission yeast. Ectopic expression of Mei4 in vegetative cells caused formation of nucleated membranous compartments, which shared common features with normal forespore membranes, thereby perturbing nuclear division. These results suggest why expression of development-specific transcription factors must be strictly controlled.
- Subjects
TRANSCRIPTION factors; CELL membranes; KARYOKINESIS; GENE expression; PROTEINS; YEAST
- Publication
Genetics, 2009, Vol 183, Issue 3, p1195
- ISSN
0016-6731
- Publication type
Article
- DOI
10.1534/genetics.109.106906