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- Title
Chronic Q-Fever (Coxiella burnetii) Causing Abdominal Aortic Aneurysm and Lumbar Osteomyelitis: A Case Report.
- Authors
Leahey, P. Alexander; Tahan, Steven R.; Kasper, Ekkehard M.; Albrecht, Mary
- Abstract
Coxiella burnetii is a rare cause of chronic infection that most frequently presents as endocarditis. We report a case of C burnetii causing an infected abdominal aortic aneurysm with contiguous lumbar osteomyelitis resulting in spinal cord compromise. The diagnosis was established by serologic studies consistent with chronic Q-fever (ratio of C burnetii immuno-globulin [Ig]G phase II titer to IgG phase I titer <1) and was confirmed by positive C burnetii polymerase chain reaction of vertebral tissue in addition to pathology of vertebral bone showing intracellular Gram-negative coccobacillary bacteria. The patient clinically improved after surgical decompression and prolonged treatment with doxycycline and hydroxychloroquine.
- Subjects
AORTIC aneurysms; COXIELLA burnetii
- Publication
Open Forum Infectious Diseases, 2016, Vol 3, Issue 1, p1
- ISSN
2328-8957
- Publication type
Case Study
- DOI
10.1093/ofid/ofv185