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- Title
Caspase-8 has an essential role in resveratrol-induced apoptosis of rheumatoid fibroblast-like synoviocytes.
- Authors
Byun, H. S.; Song, J. K.; Kim, Y.-R.; Piao, L.; Won, M.; Park, K. A.; Choi, B. L.; Lee, H.; Hong, J. H.; Park, J.; Seok, J. H.; Lee, Y. J.; Kang, S. W.; Hur, G. M.
- Abstract
Objective. Resveratrol is a naturally occurring polyphenol, which possesses chemotherapeutic potential through its ability to trigger apoptosis. The objective of this study was to investigate the major determinant for the apoptotic cell death induction by resveratrol in fibroblast-like synoviocytes (FLS) derived from patients with RA.
- Subjects
RESVERATROL; POLYPHENOLS; APOPTOSIS; CELL death; FIBROBLASTS
- Publication
Rheumatology, 2008, Vol 47, Issue 3, p301
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kem368