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- Title
Recent progress in the field of Artificial Organs.
- Abstract
A recent article in the journal Artificial Organs discusses the development of a biohybrid robotic right ventricle that accurately models the function of the native right ventricle. The robotic ventricle was tested in vitro and showed similar hemodynamic measurements to in vivo pig experiments. This technology has the potential to advance our understanding of right ventricular function, improve surgical training models, and reduce the need for animal studies. Another study from Nanjing University describes a novel approach to regenerating thyroid glands in the spleen, which could offer an alternative to lifelong medication for patients who undergo thyroidectomy. The study showed successful revascularization and functional thyroid hormone secretion in an in vivo mouse model. In other news, the FDA has granted an investigational device exemption to BiVacor for their total artificial heart, allowing them to begin a first-in-human study. The BiVacor total artificial heart uses magnetically levitated rotary pump technology and is designed to be small enough for women and most children while maintaining sufficient cardiac output. Finally, the second recipient of a genetically modified porcine heart through cardiac xenotransplantation unfortunately died due to signs of rejection. However, these transplants have provided valuable data for scientists to improve xenotransplantation and potentially reduce wait times for organ transplants.
- Subjects
ARTIFICIAL organs; HEART; PULSATILE flow; ARTIFICIAL hearts; THYROID hormones
- Publication
Artificial Organs, 2024, Vol 48, Issue 4, p322
- ISSN
0160-564X
- Publication type
Article
- DOI
10.1111/aor.14711