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- Title
Responses of human T cells to peptides flanking the tandem repeat and overlapping the signal sequence of MUC1.
- Authors
Correa, Isabel; Plunkett, Timothy; Coleman, Julia; Galani, Eleni; Windmill, Elisabeth; Burchell, Joy M.; Taylor-Papdimitriou, Joyce
- Abstract
The epithelial mucin MUC1 is one of the few tumour-associated antigens identified for breast cancer. Several MUC1-derived peptides binding HLA-A*0201 molecules have been identified that correspond to sequences outside the tandem repeat. Immunisation with some of these peptides induces protective antitumour immunity in mice. Another HLA-A*0201-binding peptide has been identified in a human system. We have evaluated the CD8
- Publication
International Journal of Cancer, 2005, Vol 115, Issue 5, p760
- ISSN
0020-7136
- Publication type
Article
- DOI
10.1002/ijc.20949