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- Title
Effect of childhood obesity prevention programmes on blood lipids: a systematic review and meta-analysis.
- Authors
Cai, L.; Wu, Y.; Cheskin, L. J.; Wilson, R. F.; Wang, Y.
- Abstract
We aimed to assess the effects of childhood obesity prevention programmes on blood lipids in high-income countries. We searched MEDLINE®, Embase, Psych Info, CINAHL®, , and the Cochrane Library up to 22 April 2013 for relevant randomized controlled trials, quasi-experimental studies and natural experiments published in English. Studies were included if they implemented diet and/or physical activity intervention(s) with ≥1 year follow-up (or ≥6 months for school-based intervention studies) in 2-18-year-olds, and were excluded if they targeted only overweight/obese children, or those with a pre-existing medical condition. Seventeen studies were finally included. For total cholesterol, the pooled intervention effect was −0.97 mg dL−1 [95% confidence interval ( CI): −3.26, 1.32; P = 0.408]; for low-density lipoprotein cholesterol ( LDL- C), −6.06 mg dL−1 (95% CI: −11.09, −1.02; P = 0.018); for high-density lipoprotein cholesterol ( HDL- C), 1.87 mg dL−1 (95% CI: 0.39, 3.34; P = 0.013); and for triglycerides, −1.95 mg dL−1 (95% CI: −4.94, 1.04; P = 0.202). Most interventions (70%) showed similar significant or no effects on adiposity- and lipids outcomes: 15% interventions improved both adiposity- and lipids outcomes; 55% had no significant effects on either. Childhood obesity prevention programmes had a significant desirable effect on LDL- C and HDL- C. Two-thirds of interventions showed similar significant or no effects in adiposity- and lipids outcomes. Assessing lipids outcomes provide additional useful information on obesity prevention programme benefits.
- Subjects
PREVENTION of childhood obesity; BLOOD lipids; RANDOMIZED controlled trials; PREVENTION of obesity; META-analysis; HIGH-income countries
- Publication
Obesity Reviews, 2014, Vol 15, Issue 12, p933
- ISSN
1467-7881
- Publication type
Article
- DOI
10.1111/obr.12227