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- Title
Fine-needle aspiration biopsy of the thyroid. The problem of suspicious cytologic findings.
- Authors
Gharib, H; Goellner, J R; Zinsmeister, A R; Grant, C S; Van Heerden, J A
- Abstract
Cases in which thyroid nodules yielded suspicious cytologic findings on fine-needle aspiration biopsy were prospectively studied during a 3-year period. Of 1970 patients, 333 (17%) had suspicious cytologic findings; from this group, the cases of 253 patients were studied. The cytologic diagnoses were 96 (38%) H urthle cell neoplasms, 84 (33%) follicular cell neoplasms, and 73 (29%) nonspecific diagnoses. A thyroid scan was obtained in 123 of 203 (61%) patients with a solitary nodule, and the nodules were hypofunctional in 102 (83%). Malignant lesions were found in 60 (24%) of the 253 patients. Our findings are consistent with reports that 20% of patients who have a fine-needle aspiration biopsy will have suspicious cytologic findings and that of these, 20% may have a malignant lesion. Thyroid scanning will not distinguish between benign and malignant thyroid lesions that are suspicious on cytologic examination. Surgical excision of all suspicious lesions seems reasonable.
- Subjects
ADENOCARCINOMA; ADENOMA; AUTOIMMUNE thyroiditis; DIFFERENTIAL diagnosis; GOITER; LONGITUDINAL method; NEEDLE biopsy; RADIONUCLIDE imaging; THYROID diseases; THYROID gland tumors; PAPILLARY carcinoma
- Publication
Annals of Internal Medicine, 1984, Vol 101, Issue 1, p25
- ISSN
0003-4819
- Publication type
journal article
- DOI
10.7326/0003-4819-101-1-25