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- Title
CHARACTERIZATION OF PEPTIDES FRACTIONS PRODUCED THROUGH ENZYMATIC HYDROLYSIS OF MEAT BYPRODUCTS FOR THEIR ANTIHYPERTENSIVE AND ANTIOXIDANT ACTIVITIES.
- Authors
Saeed, Munazza; Khan, Muhammad Issa; Butt, Masood Sadiq; Riaz, Farah
- Abstract
Meat industry produces huge amount of waste which have potential to be used as the valuable source of proteins and derived bioactive compounds. Dietary interventions have augmented the use of bioactive components with increased awareness for healthy life of individuals. Efforts have been endured to develop functional constituents that offer therapeutic responses towards physiological disorders. The current study was designed to investigate the therapeutic potential of meat byproducts hydrolysates derived after enzymatic hydrolysis with special reference to anti-hypertension and antioxidant activity. Meat byproducts were subjected to physicochemical assays and hydrolysis assessment were also carried out to estimate the release of peptides through RP-HPLC. Moreover, the hydrolysates containing bioactive peptides obtained after hydrolyses were further evaluated for antihypertensive and antioxidative activities. Liver and kidney showed higher enzymatic hydrolysis at maximum hydrolysis time. The ACE inhibitory activity of liver hydrolysate increased significantly with increase in hydrolysis time. The kidney hydrolysates have significantly higher ABTS radicals scavenging activity than liver and heart. The results indicated that hydrolysates of liver and kidney showed significantly higher oxygen radical absorbance capacity (ORAC) activity after given hydrolysis time. In conclusion, meat byproducts can be utilized for generation of functional bioactive peptides that therapeutic applications to cure human ailments.
- Subjects
HYDROLYSIS; PEPTIDES; MEAT industry; REACTIVE oxygen species; ERECTOR spinae muscles; MEAT byproducts; ANGIOTENSIN I
- Publication
Pakistan Journal of Agricultural Sciences, 2020, Vol 57, Issue 2, p545
- ISSN
0552-9034
- Publication type
Article
- DOI
10.21162/PAKJAS/19.8506