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- Title
The utility of genotypic tropism testing in clinical practice.
- Authors
Wyatt, H; Herman, OM; Macartney, M; Conibear, T; Garcia-Diaz, A; Booth, C; McCormick, A; Smith, C; Johnson, MA; Irish, D; Webster, DP
- Abstract
A review of a large number of HIV-1 tropism test requests (n = 1148) performed at a London tertiary referral centre was carried out. The aim was to establish whether these were being performed in line with recommendations from published guidelines and whether this represented the most cost-effective use of these tests in informing prescribing decisions of the CCR5 antagonist drug, maraviroc. The cost of these assays within the UK was covered by commercial funding until April 2013 which has subsequently been withdrawn. Furthermore, all healthcare settings are under increasing cost constraints and hence establishing the real utility and appropriate use of these tests is of vital importance.
- Subjects
VIRAL tropism; HIV infections; THERAPEUTICS; REFERRAL centers (Information services); MARAVIROC (Drug); ANTIRETROVIRAL agents
- Publication
International Journal of STD & AIDS, 2015, Vol 26, Issue 8, p593
- ISSN
0956-4624
- Publication type
Article
- DOI
10.1177/0956462414546917