We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prevalence of Hepatitis D Virus Infection and Associated Factors Among HBsAg-Positive Patients in Birjand, Iran, 2012 - 2014.
- Authors
Sharifzadeh, Gholamreza; Namaei, Mohammad Hasan; Ebrahimzadeh, Azadeh; Azarkar, Zohreh; Fereidouni, Mohammad; Bijari, Bita; Javanmard, Davod; Karamian, Mehdi; Farzad, Marjan; Ziaee, Masood
- Abstract
Background: It is estimated that about 5% of hepatitis B surface antigen (HBsAg) carriers are infected with hepatitis D virus (HDV) worldwide. Moreover, dual infection with hepatitis B virus (HBV) / HDV causes more severe diseases and leads to a higher risk of mortality. Objectives: This study was performed to determine the prevalence of HDV infection and identify HDV-associated factors among HBsAg-positive patients in Birjand, South Khorasan province, Iran. Methods: This descriptive, cross sectional study was conducted on 5235 participants in line with a previous study on the seroprevalence of HBV in South of Khorasan. HDV was assessed through evaluating the blood serum of diagnosed HBsAg-positive patients (85 cases) by ELISA test. For statistical analysis, descriptive statistics were calculated, using SPSS version 22. Results: In this study, the mean age of HBsAg-positive patients was 45.1 ± 12.9 years (minimum, 22 years; maximum, 70 years). In total, 1 out of 85 cases was positive for HDV virus. The prevalence of HDV infection among HBsAg-positive patients was 1.2% (95% CI, - 1.2 to 3.5). Conclusions: The low prevalence of HDV infection in South of Khorasan was remarkable, considering the great area of this province, use of a comprehensive and inclusive sampling strategy, and mutual borders with Afghanistan.
- Subjects
IRAN; CONFIDENCE intervals; ENZYME-linked immunosorbent assay; HEPATITIS D; HEPATITIS B; RESEARCH methodology; VIRAL antigens; DISEASE prevalence; CROSS-sectional method; DATA analysis software; DESCRIPTIVE statistics; MIXED infections; DIAGNOSIS
- Publication
Hepatitis Monthly, 2017, Vol 17, Issue 5, p1
- ISSN
1735-143X
- Publication type
Article
- DOI
10.5812/hepatmon.42866