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- Title
Effectiveness and usability of short-time treatment of psoriasis vulgaris with two different corticosteroids under occlusion with a hydrocolloid dressing (Contreet[supR]).
- Authors
Faber, W.R.; van Joost, Th.; de Hoop, D.; Berretty, P.J. M.; Boelen, R. E.; Neumann, H. A. M.
- Abstract
Objectives: To evaluate the efficacy of treatment of plaque-type psoriasis with a moderate and a strong corticosteroid under continuous hydrocolloid occlusion, with weekly change of dressing, compared with treatment with the same corticosteroids alone, and the acceptance by the patients of his type of treatment. Setting: Dermatological Departments of two University Hospitals and four General Hospitals. Design: Open parallel study divided in two parts depending on the two different corticosteroid preparations applied. Each part was an intrasubject half-side study with left-right comparison. Subjects: Fifty five patients with symmetrical, stable psoriasis plaques on elbows or knees. Methods: Twenty nine patients were treated with clobetason butyrate cream (Emovate[supR]) twice daily as well as once weekly covered with a hydrocolloid dressing (Contreet[supR]) for four weeks. Twenty six patients were treated with clobetasol propionate cream (Dermovate[supR]) twice daily as well as once weekly covered by the hydrocolloid dressing for 2 weeks. Induration, erythema and scaling were assessed using a four-point scale. Plaque size was measured by multiplying the largest and the smallest diameter. Healing was defined as score 0 for scaling and induration and score 0 or 1 for erythema. Acceptance was evaluated by questions related to the wearing of the dressings; comfort of wearing, pain, itching, adhesiveness and sticking to clothing, and the performance of daily activities. Statistics analysis: Sign test for the score values, parametric paired Student I-test for plaque size, chi-square test for healing.
- Subjects
THERAPEUTICS; PSORIASIS treatment; CORTICOSTEROIDS; HYDROCOLLOID surgical dressings; ERYTHEMA; HYDROCOLLOIDS
- Publication
Journal of the European Academy of Dermatology & Venereology, 1995, Vol 5, Issue 2, p157
- ISSN
0926-9959
- Publication type
Article
- DOI
10.1111/j.1468-3083.1995.tb00537.x