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- Title
BOALA VASCULARĂ ÎN LUPUSUL ERITEMATOS SISTEMIC: ÎNTREPĂTRUNDERE A FACTORILOR DE RISC TRADIȚIONALI ŞI NETRADIȚIONALI.
- Authors
Săulescu, Ioana; Furtunescu, Florentina; Opriş, Daniela; Groseanu, Laura; Borangiu, Andreea; Constantinescu, Cosmin; Negru, Magda; Ionescu, Ruxandra
- Abstract
Background. Systemic lupus erythematosus is affecting young people with a big impact on the quality of life, life expectancies and co-morbidities. Although vascular involvement is not the most common, in time atherosclerotic complications are related to increasing mortality. Objective. To characterized our SLE cohort from the cardiovascular events perspective, in order to improve our prevention strategies. Material and methods. We evaluated 65 patients with SLE admitted in SF Maria Hospital between october 2012 - april 2013. All patients gave informed consent for all procedures. We performed a complete evaluation of all patients both clinical and paraclinical, including disease activity score - SLEDAI, damage score - SLICC damage index, history of the disease and medication, cardiovascular disease. Results. The statistic analysis was made with SPSS for Windows Xp, with a double analysis: descriptive and analytical. Almost half of the patients - 49% had at least one cardiovascular event, most of them being older then 45 years. 68.75% from 32 patients with cardiovascular disease had positive ds DNA AB. 87.5 % from this patients had a disease longer then 5 years (p < 0.05) and 65.62% had a SLICC greater or equal with 1 (p < 0.05). Conclusion. Cardiovascular involvement, mainly atherosclerosis, is now an important cause of morbidity and mortality in SLE. Routine assessment for this pathology should be implemented in order to improve quality of life and survival, especially in long standing disease that already accumulated damage.
- Publication
Romanian Journal of Pediatrics / Revista Romana de Pediatrie, 2014, Vol 63, Issue 2, p63
- ISSN
1454-0398
- Publication type
Article