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- Title
Reinventing phage therapy: are the parts greater than the sum?
- Authors
Fischetti, Vincent A.; Nelson, Daniel; Schuch, Raymond
- Abstract
The article compares the therapeutic use of whole phages and purified phage antibacterial agents as an alternative to antibiotics for the treatment and control of antibiotic resistant bacterial pathogens. The process of phage therapy, the United States Food and Drug Administration's regulatory approval and patent protection constraints are discussed. The article also discusses the scope for lysin development as an antibacterial component in humans, agriculture and food control applications.
- Subjects
THERAPEUTIC use of bacteriophages; ANTIBACTERIAL agents; PATHOGENIC bacteria; ANTIBIOTICS; REGULATORY approval; PATENT law; DRUG resistance in microorganisms; UNITED States. Food &; Drug Administration; PREVENTION; THERAPEUTICS
- Publication
Nature Biotechnology, 2006, Vol 24, Issue 12, p1508
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt1206-1508