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- Title
A BRIEF ORIGINAL CONTRIBUTION.
- Authors
Matheson, Pamela B.; Weedon, Jeremy; Cappelli, Mark; Abrams, Elaine J.; Shaffer, Nathan; Bamji, Mahrukh; Krasinski, Keith; Lambert, Genevieve; Kaul, Aditya; Grimm, Katherine; Hutson, David; Thomas, Pauline A.
- Abstract
Four methods of estimating mother-to-child transmission rates of human immunodeficiency virus type 1 (HIV-1), based on the 1992 Ghent workshop, were compared in a multicenter New York City prospective cohort study in 1986–1992. Of 833 infants born to women at risk of HIV-1 infection, 388 were born HIV-1 seropositive and 445 were HIV-1 seronegative. The four methods, the Antibody Only, Indirect, Direct, and Virologic Methods, yielded transmission rate estimates of 19–25%, classifying 59–89% of the cohort. Estimation based on persistence of HIV-1 antibody and clinical assessment yielded transmission rates similar to those methods that incorporated virologic testing. 1995;142:714–18.
- Publication
American Journal of Epidemiology, 1995, Vol 142, Issue 7, p714
- ISSN
0002-9262
- Publication type
Article
- DOI
10.1093/oxfordjournals.aje.a117701