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- Title
The Menstrual Cycle.
- Authors
Hawkins, Shannon M.; Matzuk, Martin M.
- Abstract
The basic biology of the menstrual cycle is a complex, coordinated sequence of events involving the hypothalamus, anterior pituitary, ovary, and endometrium. The menstrual cycle with all its complexities can be easily perturbed by environmental factors such as stress, extreme exercise, eating disorders, and obesity. Furthermore, genetic influences such as fragile X premutations, X chromosome abnormalities, and galactose-1-phosphate uridyltransferase (GALT) point mutations (galactosemia) also contribute to perturbations of the menstrual cycle. Although not perfect, mouse models have helped to identify and confirm additional components and pathways in menstrual cycle function and dysfunction in humans.
- Subjects
WOMEN'S health; X chromosome abnormalities; MENSTRUAL cycle; APPETITE disorders; SEX chromosomes; HEALTH education of women; DISEASES in women; NUTRITION disorders; APPETITE loss; EATING disorders
- Publication
Annals of the New York Academy of Sciences, 2008, Vol 1135, p10
- ISSN
0077-8923
- Publication type
Article
- DOI
10.1196/annals.1429.018