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- Title
Practice guidelines for therapeutic drug monitoring of voriconazole: a consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring.
- Authors
Hamada, Yukihiro; Tokimatsu, Issei; Mikamo, Hiroshige; Kimura, Masao; Seki, Masafumi; Takakura, Shunji; Ohmagari, Norio; Takahashi, Yoshiko; Kasahara, Kei; Matsumoto, Kazuaki; Okada, Kenji; Igarashi, Masahiro; Kobayashi, Masahiro; Mochizuki, Takahiro; Nishi, Yoshifumi; Tanigawara, Yusuke; Kimura, Toshimi; Takesue, Yoshio
- Abstract
The article discusses the practice guidelines which review the factors influencing the voriconazole (VRCZ) pharmacokinetic profile conducted by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring (JSTDM). It examines the data that support exposure-toxicity and exposure-effect relationships that cause difficulty for therapeutic drug monitoring for VRCZ. It also mentions indications for VRCZ therapeutic drug monitoring (TDM).
- Subjects
PHARMACOKINETICS; ANTIFUNGAL agents; DRUG monitoring; TOXICITY testing; MYCOSES; COMMUNICABLE disease treatment
- Publication
Journal of Infection & Chemotherapy (Springer Science & Business Media B.V.), 2013, Vol 19, Issue 3, p381
- ISSN
1341-321X
- Publication type
Article
- DOI
10.1007/s10156-013-0607-8