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- Title
Bowel perforations in a patient affected by Churg-Strauss syndrome under high-dose steroid treatment: will alternative drugs reduce risk of surgery?
- Authors
Venditti, Dario; Valerio, Balassone; Ielpo, Benedetto; Buonomo, Oreste; Petrella, Giuseppe
- Abstract
Churg-Strauss syndrome is a relapsing-remitting vasculitis that frequently involves digestive system. Ischemic perforation of the large bowel is relatively rare and potentially life threatening. We report a case treated with high dose of steroids for a relapsing of Churg-Strauss vasculopathy that underwent emergency surgery for multiple large-bowel perforations. Massive use of steroids is common for controlling relapse of this disease, but this increases the risk of intestinal perforation. A prompt switching to alternative drugs when intestinal tract is involved should be considered in order to prevent surgery.
- Subjects
CASE studies; CHURG-Strauss syndrome; VASCULITIS; STEROID drugs; INTESTINAL surgery
- Publication
Rheumatology International, 2011, Vol 31, Issue 9, p1239
- ISSN
0172-8172
- Publication type
Report
- DOI
10.1007/s00296-009-1289-5