We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Development of antisynthetase syndrome in a patient with rheumatoid arthritis.
- Authors
Cheol-Kyu Park; Tae-Jong Kim; Young-Nan Cho; Il-Soo Kim; Ho-Jun Lee; Kyung-Eun Lee; Seong-Chang Park; Jong-Sun Kim; Dong-Jin Park; Sung-Ji Lee; Seong-Rye Seo; Jeong-Chul Kim; Sang-Gook Song; Shin-Seok Lee; Yong-Wook Park
- Abstract
Rheumatoid arthritis (RA) and antisynthetase syndrome (ASS) are distinct clinical syndromes, and their co-occurrence is rarely encountered. The authors report the case of a 56-year-old female patient with RA of 3 years duration who suddenly developed ASS, and include a review of the literature. The patient was diagnosed with ASS based on; positivity for anti-histidyl-tRNA synthetase (Jo-1) antibody, interstitial lung disease, polyarthritis, and mechanic's hands. High-dose corticosteroid and pulse intravenous cyclophosphamide were used to control the ASS. This case demonstrates that ASS should be considered during clinical presentations due to its potential overlap with RA.
- Subjects
RHEUMATOID arthritis; AUTOIMMUNE diseases; CYCLOPHOSPHAMIDE; ANTIRHEUMATIC agents; JOINT diseases
- Publication
Rheumatology International, 2011, Vol 31, Issue 4, p529
- ISSN
0172-8172
- Publication type
Report
- DOI
10.1007/s00296-009-1222-y