Presents a study that showed that the parathyroid hormone 1 receptor (PTH1R) binds to Na[sup+]/H² exchanger regulatory factors (NHERF) 1 and 2 through a PDZ-domain interaction in vitro and in PTH target cells. Effect of PTH treatment of cells; NHERF-mediated assembly of PTH1R and phospholipase C β ; Function of the PDZ domains of NHERF2.