We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A Case of Adult Metastatic Rhabdomyosarcoma of the Prostate Cured by Long-Term Chemotherapy with Local Radiation.
- Authors
Konno, Masato; Mitsuzuka, Koji; Yamada, Shigeyuki; Yamashita, Shinichi; Kaiho, Yasuhiro; Ito, akihiro; Watanabe, Mika; arai, Yoichi
- Abstract
A 32-year-old man visited our hospital due to urinary retention. Prostate-specific antigen was 13.7 ng/mL. Imaging examinations showed a large prostatic tumor and lung and internal iliac lymph node metastases. Transrectal biopsy confirmed embryonal rhabdomyosarcoma of the prostate classified as cT2bN1M1 (stage IV) by the International Rhabdomyosarcoma Study (IRS) Group staging system. Systemic chemotherapy was started according to the IRS III regimen 36, which consisted of 16 weeks of induction chemotherapy with radiation. After 20 weeks, magnetic resonance imaging showed the disappearance of metastases, and the prostate tumor shrunk markedly. Moreover, prostatic re-biopsy showed no viable tumor cells. Maintenance chemotherapy, excluding vincristine because of severe peripheral nerve disorder, was performed for 2 years. There has been no recurrence for 49 months after the termination of maintenance chemotherapy. To the best of our knowledge, this is the longest surviving case of adult-onset metastatic rhabdomyosarcoma of the prostate reported in the literature.
- Subjects
RHABDOMYOSARCOMA; CANCER chemotherapy; RADIOTHERAPY; LOCAL radiation effects; METASTASIS; RETENTION of urine; PROSTATE-specific antigen; LYMPH nodes
- Publication
Urologia Internationalis, 2019, Vol 102, Issue 1, p118
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000473861