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- Title
Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta.
- Authors
Topham, Matthew K.; Bunting, Michaeline; Zimmerman, Guy A.; McIntyre, Thomas M.; Blackshear, Perry J.; Prescott, Stephen M.
- Abstract
Presents research which showed that a fraction of diacylglycerol kinase (DGK)-zeta is found in the nucleus. Role of DGKs; Effects of DGK-zeta in the nucleus; Impact of reducing nuclear diacylglycerol levels; Nuclear-localization signal of DGK-zeta and its regulation; Cycle in which diacylglycerol activates protein kinase C; Nuclear diacylglycerol and the control of mitogenic signals.
- Subjects
PROTEIN kinase C; CELL nuclei; CELLULAR control mechanisms; MITOGENS; BIOCHEMICAL mechanism of action; PHYSIOLOGY
- Publication
Nature, 1998, Vol 394, Issue 6694, p697
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/29337