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- Title
Carbon nanomaterials as electrode surface modifiers in development of amperometric monoamino oxidase biosensors.
- Authors
Brusnitsyn, D.; Medyantseva, E.; Varlamova, R.; Sitdikova, R.; Fattakhova, A.; Konovalova, O.; Budnikov, G.
- Abstract
Modification of a printed graphite electrode surface by carbon nanomaterials (carbon nanotubes and graphene oxide) was used to improve the analytical capabilities of amperometric monoamine oxidase biosensors in the determination of medicinal substances with antidepressant activity (moclobemide and amitriptyline). It was found that the range of determined concentrations of pharmaceutical agents varied from 1 × 10 to 1 × 10 mol/L. The developed monoamine oxidase biosensors were used for determination of medicinal agents in their dosage forms.
- Subjects
CARBON nanotubes; GRAPHITE; ELECTRODE design &; construction; AMPEROMETRIC sensors; MOCLOBEMIDE
- Publication
Inorganic Materials, 2016, Vol 52, Issue 14, p1413
- ISSN
0020-1685
- Publication type
Article
- DOI
10.1134/S002016851614003X