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- Title
Metastasis: Route master.
- Authors
McCarthy, Nicola
- Abstract
The article reports on a study by Don Nguyen and Joan Massagué which discovers that Wnt pathway is significant for lung adenocarcinoma metastasis to the brain and bone. Researchers test lung adenocarcinoma samples for gene expression signatures that correspond several activated pathways. They hypothesize that Wnt pathway could be activated in lung adenocarcinoma by the expression of Wnt ligands.
- Subjects
METASTASIS; ADENOCARCINOMA; LUNG cancer &; genetics; GENE expression; MASSAGUE, Joan; NGUYEN, Don; GENETICS; PROTEINS; LUNG tumors; CELLULAR signal transduction; GLYCOPROTEINS; ANIMALS
- Publication
Nature Reviews Cancer, 2009, Vol 9, Issue 9, p610
- ISSN
1474-175X
- Publication type
journal article
- DOI
10.1038/nrc2721