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- Title
Multiple myeloma: Establishing order from chaos.
- Authors
McCarthy, Nicola
- Abstract
The article discusses the findings of a study conducted by Ron DePinho and colleagues regarding the cancer-associated changes in multiple myeloma. The authors used high-resolution array comparative genomic hybridization to identify copy-number aberrations in plasma cells from 67 newly diagnosed patients with MM.They provided evidence of the biological significance of the k1 and k2 subclasses by gene-set enrichment analysis of the relevant transcriptomes.
- Subjects
MULTIPLE myeloma; CANCER research; CANCER patients; PLASMA cells; ONCOGENES; DEPINHO, Ron
- Publication
Nature Reviews Cancer, 2006, Vol 6, Issue 5, p339
- ISSN
1474-175X
- Publication type
Article
- DOI
10.1038/nrc1899