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- Title
Electroretinograms in three cases of Creutzfeldt-Jakob disease with visual disturbances.
- Authors
Akira Ishikawa; Atsuhiro Tanikawa; Yoshiaki Shimada; Tatsuro Mutoh; Hiroko Yamamoto
- Abstract
Abstract Purpose To report three cases of idiopathic Creutzfeldt-Jakob disease (CJD) with visual symptoms. Cases Patient 1 initially visited our ophthalmology department complaining of blurred vision. Electro-retinography (ERG) showed a selective reduction of the b wave before she was diagnosed with CJD. Patient 2 had normal ERG results even with severely advanced CJD. However, a reduction of the b wave on ERG was observed 1 month before the patient died. Patient 3 had visual disturbances at the initial visit, but the ERG result was normal even after the CJD had advanced. Atrophy of the visual cortex was later observed. Observations CJD can alter the vision in various ways. The selective reduction of the b wave on ERG indicates the retinal involvement. However, visual disturbances may occur without the retinal implications. Conclusion Ophthalmologists should be aware that the visual impairment can be the first symptom of CJD.
- Subjects
ELECTRORETINOGRAPHY; VISION disorders; OPHTHALMOLOGY; MUSCULAR atrophy; VISUAL cortex
- Publication
Japanese Journal of Ophthalmology, 2009, Vol 53, Issue 1, p31
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-008-0608-9