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- Title
内镜下黏膜切除术治疗胃息肉的疗效及对血清ProGRP、 PGI 水平的影响.
- Authors
华婷琰; 华娴; 闵寒; 杨建龙; 陆筱祎
- Abstract
Objective: To investigate the efficacy of endoscopic mucosal resection in the treatment of gastric polyps and its effect on the levels of serum gastrin releasing peptide precursor (ProGRP) and pepsinogen I (PGI). Methods: 120 patients with gastric polyps admitted in our hospital from August 2019 to August 2022 were selected as the research objects, and were divided into groups according to different surgical methods. Among them, 60 patients who were treated with conventional endoscopic electrocoagulation were divided into the control group, and 60 patients who were treated with endoscopic mucosal resection were divided into the observation group. The occurrence of adverse effects and treatment costs between the two groups, serum ProGRP, PGI expression levels and inflammatory factors expression levels before and after surgery, and the overall resection rate and complications in the two groups were compared. Results: There was no difference in the total treatment costs between the two groups (P > 0.05) . The incidence of postoperative adverse effects in the observation group was lower than that in the control group (P < 0.05) ; There was no difference in serum ProGRP and PGI levels between the two groups before operation (P > 0.05) After treatment, the ProGRP and PGI levels of the two groups decreased, and the observation group was lower than the matched group (P < 0.05) ; There was no difference in PCT, CRP, IL-6 and IL-2 between the two groups before operation (P > 0.05) After operation, PCT, CRP, IL-6 and IL-2 of the two groups increased, and the observation group was lower than the matched group (P < 0.05) ; The gastric polyps were completely removed in both groups, and the overall resection rate was not different, and the incidence of perforation, delayed bleeding and infection was lower than that of the control group, but the difference was not significant (P > 0.05) Conclusion: Both endoscopic mucosal resection and conventional endoscopic electrocoagulation can completely remove gastric polyps in patients with gastric polyps, and the treatment cost is equivalent. The application of endoscopic mucosal resection can reduce the levels of ProGRP and PGI in patients, reduce the inflammatory reaction of the body, and have a low incidence of complications, which is worthy of clinical application and promotion
- Subjects
ENDOSCOPIC surgery; PEPTIDES; POLYPECTOMY; GASTRECTOMY; PEPSINOGEN; CLINICAL medicine
- Publication
Progress in Modern Biomedicine, 2023, Vol 23, Issue 9, p1731
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2023.09.026