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- Title
TIP 2 DIJABETES MELITUS U DJECE I ADOLESCENATA.
- Authors
VLAŠKI, JOVAN; VORGUČIN, IVANA
- Abstract
Diabetes mellitus type 2 is the most common form of diabetes in adults and accounts for around 90% of all diabetes cases. While type 1 diabetes mellitus remains the most common form of diabetes in young people. Type 2 diabetes, once known as adult-onset or noninsulin-dependent diabetes. Type 2 diabetes is heterogeneous disorder. The aim of this paper was to give epidemiological and clinical characteristics of type 2 diabetes in children and adolescents. Essential elements are disturbed insulin secretion, with previous insulin resistance and obesity. When the insulin secretion is below 85% then occurs a typical clinical picture in children and adolescents. Obesity and insulin resistance also affect inflammatory response, antigen exposure, and apoptosis of β-pancreatic cells. This is confirmed by presence of antibodies that are typical for type 1 diabetes in more than 15%. The aim of our work was to determine the incidence of type 2 diabetes in children and adolescents that were treated in the Institute for Children and Youth Health Care of Vojvodina in Novi Sad. This was a retrospective study, using medical archive dana, during 34 ages (1980-2014) and a prospective study (2015-2017) that included 200 obese children aged 10-18 years who had a Body Mass Index above 97 percent. Fasting plasma glucose was determine, OGTT and HbA1c. The results showed that there was no any case of type 2 diabetes except one extremely 14-years-old obese boy, who was detected as diabetic ketoacidosis. In only four adolescents, there was impaired glucose tolerance, which is only 2% of the target sample. In conclusion, we described pre-diabetic state, as a field where preventive activity is most useful and necessary.
- Subjects
NOVI Sad (Serbia); VOJVODINA (Serbia); TYPE 1 diabetes; DIABETES in children; ADOLESCENCE; YOUTH; DIABETIC acidosis; TYPE 2 diabetes
- Publication
Paediatria Croatica, Supplement, 2019, Vol 63, p42
- ISSN
1330-724X
- Publication type
Article