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- Title
Editorial: Footprints of immune cells in the type 1 diabetic pancreas, volume II.
- Authors
Christoffersson, Gustaf; Fousteri, Georgia
- Abstract
This article is an editorial discussing the role of immune cells in type 1 diabetes (T1D) and their impact on the pancreas. The authors highlight the importance of studying immune cells in the pancreas itself, as peripheral measurements may not accurately reflect the conditions in the organ. The editorial also discusses the hyperexpression of HLA-I in T1D pancreas and the potential role of interferons in driving this upregulation. Additionally, the article explores the interplay between peripheral neurons and immune cells in T1D and the potential use of N-glycosylated complement component C3 as a biomarker for T1D progression. The authors emphasize the need for a comprehensive approach to understanding T1D and developing new therapeutics and biomarkers.
- Subjects
FOOTPRINTS; PANCREAS; INTERFERON receptors; TYPE 1 diabetes; DORSAL root ganglia
- Publication
Frontiers in Endocrinology, 2024, p1
- ISSN
1664-2392
- Publication type
Article
- DOI
10.3389/fendo.2024.1367245