We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
INVITRO EVALUATION OF SELECTED ANTIOXIDANTS, VITAMINS AND MINERALS BY USING MODIFIED ARTIFICIAL STOMACH MODEL.
- Authors
Shah, Darshan; Mz, Nitin; Raot, A. Srinivasa
- Abstract
The investigation was aimed to explore the In vitro effect of few selected antioxidants, vitamins and minerals. A modified artificial stomach model was performed as per established method and variousparameters like, Preparation of artificial gastric acid, pH determination of test drugs, determination of the neutralization effects on artificial gastric acid, determination of the duration of consistent neutralization on artificial gastric acid using the modified model of Vatier's artificial stomach were studied. All ~, test groups and sodium bicarbonate have significant acid neutralizing 4 effects when compared with water. The duration for consistent L neutralization and antacid capacities of all test groups were significantly higher than of water (control). The In vitro study shows all test groups were consistently active in the artificial stomach model and possess gastroprotection.
- Subjects
ANTIOXIDANTS; GASTRIC acid; BIOLOGICAL models; ACID neutralizing capacity; ANTACIDS; MINERAL analysis; EVALUATION
- Publication
Advances in Pharmacology & Toxicology, 2018, Vol 19, Issue 1, p27
- ISSN
0973-2381
- Publication type
Article