We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pseudoprogression of Malignant Peripheral Nerve Sheath Tumor in Patient with Neurofibromatosis Type 1, a Case Report.
- Authors
Lessing, Andrés J.; Cote, Gregory M.; DeLaney, Thomas F.; Plotkin, Scott R.; Raskin, Kevin A.; Lessing, Juan N.
- Abstract
Pseudoprogression, defined as the radiographic false appearance of disease progression, is not frequently observed in patients with malignant peripheral nerve sheath tumor (MPNST). We report on a case of a patient with neurofibromatosis type 1 (NF1) MPNST pseudoprogression that presented as suspected local recurrence 9.5 years after last treatment. The patient underwent surgical resection following growth of a mass on sequential MRI imaging; surgical pathology, however, showed skeletal muscle with atrophy, fibroadipose tissue, and fat necrosis, without any evidence of tumor. As MPNST survival rates increase, physicians should consider pseudoprogression as a potential presentation after prior treatment.
- Subjects
PERIPHERAL nerve tumors; SCHWANNOMAS; NEUROFIBROMATOSIS 1; MAGNETIC resonance imaging
- Publication
Case Reports in Oncology, 2021, Vol 14, Issue 3, p1342
- ISSN
1662-6575
- Publication type
Case Study
- DOI
10.1159/000518317