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- Title
Growth inhibition and morphological alterations of Staphylococcus aureus caused by the essential oil of Aloysia triphylla.
- Authors
de las M OLIVA, María; CAREZZANO, Evangelina; GALLUCCI, Nicolas; FREYTES, Sebastian; ZYGADLO, Julio A.; DEMO, Mirta-Susana
- Abstract
Aloysia triphylla essential oil (EO) has antimicrobial activity on Staphylococcus aureus which is a pathogen responsible for severe infections and food contamination. The target of EO is mainly in the cytoplasmic membrane. In this work the mechanisms of action of the EO of A. triphylla on S. aureus were investigated. A. triphylla was collected from La Paz. The oil was analyzed by GC-MS. The antimicrobial effects were evaluated by MIC, MBC, killing time and TEM. MIC values were 23 μg/mL for 6.3 x 104 CFU/mL, 92 μg/mL for 5.71 x 105 CFU/mL and 180 μg/mL for 9 x 106 CFU/mL. The MBC was 5920 μg/mL for all cellular concentrations and it was necessary more time to kill bigger cell populations. Multilamellar and mesosome-like structures on the membrane were seen by TEM. A. triphylla oil is an antibacterial compound against S. aureus which main mechanism of action seems to be the cytoplasmic membrane disruption.
- Subjects
ESSENTIAL oils; VERBENA; STAPHYLOCOCCUS aureus
- Publication
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, 2015, Vol 14, Issue 2, p83
- ISSN
0717-7917
- Publication type
Article