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- Title
Stimulation of Reparative Processes in Cartilage Defects in Rabbits Using AD (DIEE) Type Biophytomodulators.
- Authors
CrecÂn, Cristian; Oros, Daniela; DincĂ, Ancu; BolfĂ, Pompei; Oana, Liviu; Bel, Lucia; PeŞtean, Cosmin; Ober, Ciprian
- Abstract
The healing of cartilage lesions is a long process due to the lack of vascularization and the particular nutrition in this type of tissue. This study aims to histologically evaluate the healing preocess of lesions inflicted in the stifle joint cartilage of rabbits, then treated with AD (DIEE) type biophytomodulators. The study was performed on 33 rabbits of German Giant breed, aged 8 months. The animals were divided into 4 groups: a group of animals treated with AD (DIEE) type biophytomodulators (BF), an untreated control group (M) and two control groups treated with hyaluronic acid (H, HS), standard therapy for such pathology. There cartilage samples were collected at 14, 30 and 90 days post-operatively, and were then histologically stained (haematoxylin and eosin) and examined under light microscopy. The results obtained showed the presence of fibrous tissue at the lesion sites and the development of more advanced healing processes in the BF group compared to the untreated control group
- Subjects
RABBIT diseases; LABORATORY rabbits; HYALURONIC acid; EOSIN; MUCOPOLYSACCHARIDES
- Publication
Bulletin of the University of Agricultural Sciences & Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2012, Vol 69, Issue 1/2, p87
- ISSN
1843-5270
- Publication type
Article