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- Title
Relationship between COVID-19 and antimicrobial resistance.
- Authors
MUDERRIS, Tuba; KAYA, Selcuk; BAYINDIR BILMAN, Fulya; OZMEN, Erkan; PEKER, Bilal Olcay; AKSOY GOKMEN, Aysegul; YURTSEVER, Sureyya Gui
- Abstract
Objective: Bacterial and fungal infections, antimicrobial resistance (AMR) results of bacterial agents, and the effect of the pandemic on AMR were evaluated in hospitalized COVID-19 patients. In addition, the detected AMR rates were compared with the AMR rates of the pre-pandemic period. Patients and Methods: The isolates grown in respiratory and blood samples of adult patients hospitalized with the diagnosis of COVID-19 between March 2020 and December 2020 were evaluated retrospectively. The same data in hospitalized patients before the pandemic, between March and December 2019, were evaluated retrospectively. Results: A total of 724 samples were included in the study. The superinfection rate was found to be 15.3%. The most frequently isolated microorganisms are; Acinetobacter baumannii (34.4%), Staphylococcus aureus (10.8%), Klebsiella pneumoniae (9.7%) and Pseudomonas aeruginosa (7.3%). The lowest resistance rates in Klebsiella pneumoniae isolates were found for aminoglycosides, in Acinetobacter baumannii isolates were found for trimethoprim-sulfamethoxazole, in Pseudomonas aeruginosa isolates were found for amikacin. When pre-pandemic and pandemic AMR rates were compared; a significant increase in amikacin resistance was detected only in Klebsiella pneumoniae isolates during the pandemic period (P:0.049). Conclusion: The data we have presented may help clinicians in the selection of antimicrobials for empirical therapy by revealing the effect of the pandemic on AMR.
- Subjects
COVID-19; ACINETOBACTER infections; CO-trimoxazole; CHLAMYDIALES; ANTI-infective agents; RETROSPECTIVE studies; ACQUISITION of data; SUPERINFECTION; AMINOGLYCOSIDES; KLEBSIELLA infections; COMPARATIVE studies; MYCOSES; HOSPITAL care; MEDICAL records; STAPHYLOCOCCUS aureus; PSEUDOMONAS diseases; DRUG resistance in microorganisms; BACTERIAL diseases; ADULTS
- Publication
Marmara Medical Journal, 2023, Vol 36, Issue 3, p312
- ISSN
1019-1941
- Publication type
Article
- DOI
10.5472/marumj.1367895