We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Renal cortical necrosis complicating laundry detergent ingestion.
- Authors
Riella, Leonardo Vidal; Golla, Sunitha; Dogaru, Grigore; Rennke, Helmut G.; Christopher, Kenneth
- Abstract
Accidental oral detergent ingestion usually causes mild gastrointestinal manifestations including nausea, vomiting and diarrhea as well as upper airway irritation. There are a limited number of reported oral detergent ingestions leading to acute kidney injury, mainly due to rhabdomyolysis. We present an ultimately fatal case of laundry detergent ingestion leading to biopsy proven severe cortical necrosis and irreversible renal damage. Detergent ingestion was associated with widespread endothelial injury leading to a picture of thrombotic microangiopathy. Among the detergent ingredients ingested by the patient, sodium borate raised the highest concern as a potential toxin exacerbated further by severe hypovolaemia and consequent decrease in renal toxin excretion. As sodium borate is dialyzable, haemodialysis should be a consideration early after laundry detergent ingestion.
- Subjects
NECROSIS; DETERGENTS; INGESTION; BIOPSY; KIDNEY diseases; HEMODIALYSIS
- Publication
NDT Plus, 2009, Vol 2, Issue 1, p40
- ISSN
1753-0784
- Publication type
Article
- DOI
10.1093/ndtplus/sfn178