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- Title
Protective efficacy of BCG vaccine against leprosy in southern Malaŵi.
- Authors
Baker, D M; Nguyen-Van-Tam, J S; Smith, S J
- Abstract
This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malaŵi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.
- Publication
Epidemiology & Infection, 1993, Vol 111, Issue 1, p21
- ISSN
0950-2688
- Publication type
journal article
- DOI
10.1017/S0950268800056636