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- Title
S1PR2: A Fulcrum in the Balance of Type 1 and Type 2 Responses during Sepsis-induced Acute Lung Injury.
- Authors
Verhoef, Philip A.
- Abstract
The article informs about the balance between type 1 and type 2 immune responses during sepsis-induced acute lung injury, highlighting the potential role of S1PR2 in regulating this balance. Topic include through experiments in mouse models and analysis of patient data, the authors suggest that S1PR2 expression on pulmonary macrophages may modulate type 2 responses during sepsis-induced lung injury, with implications for potential therapeutic interventions.
- Subjects
LUNG injuries; PHAGOCYTOSIS; TH2 cells
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2024, Vol 70, Issue 3, p157
- ISSN
1044-1549
- Publication type
Article
- DOI
10.1165/rcmb.2023-0433ED