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- Title
Neurodevelopment of Infants with Prenatal Exposure to Polybrominated Diphenyl Ethers.
- Authors
Shy, Cherng-Gueih; Huang, Huei-Lin; Chang-Chien, Gou-Ping; Chao, How-Ran; Tsou, Tsui-Chun
- Abstract
The study aimed to examine the impact of prenatal exposure to polybrominated diphenyl ethers (PBDEs) on infant neurodevelopment. PBDEs levels in 36 cord blood samples were analyzed with a high-resolution-gas-chromatograph/high-resolution-mass-spectrometer and infant neurodevelopment was assessed using the Bayley Scales of Infant and Toddler Development, Third Edition. The mean and median of ΣPBDEs were 6.63 and 4.63 ng/g lipid, respectively. As compared to the lower PBDEs group (ΣPBDEs < 4.63 ng/g lipid), the higher PBDEs group (ΣPBDEs > 4.63 ng/g lipid) had a significantly higher actual odds ratio (OR = 1.13, p < 0.05) of the cognition score as well as a lower odds ratio (OR = 0.904, p < 0.01) of the adaptive behavior score, suggesting that prenatal PBDEs exposure may potentially affect infant neurodevelopment.
- Subjects
TAIWAN; PHYSIOLOGICAL effects of polybrominated diphenyl ethers; EFFECT of drugs on infants; INFANT development; COGNITION in infants; CORD blood; BAYLEY Scales of Infant Development; MATERNAL age
- Publication
Bulletin of Environmental Contamination & Toxicology, 2011, Vol 87, Issue 6, p643
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s00128-011-0422-9