We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Hypoxic ventilatory response is correlated with increased submaximal exercise ventilation after live high, train low.
- Authors
Townsend, Nathan E; Gore, Christopher J; Hahn, Allan G; Aughey, Robert J; Clark, Sally A; Kinsman, Tahnee A; McKenna, Michael J; Hawley, John A; Chow, Chin-Moi
- Abstract
This study tested the hypothesis that live high, train low (LHTL) would increase submaximal exercise ventilation (V(E)) in normoxia, and the increase would be related to enhanced hypoxic ventilatory response (HVR). Thirty-three cyclists/triathletes were divided into three groups: 20 consecutive nights of hypoxia (LHTLc, n = 12), 20 nights of intermittent hypoxia (4x5-night 'blocks' of hypoxia interspersed by two nights of normoxia, LHTLi, n = 10), or control (CON, n = 11). LHTLc and LHTLi slept 8-10 h per night in normobaric hypoxia (2,650 m), and CON slept under ambient conditions (600 m). Resting, isocapnic HVR (DeltaV(E)/Deltablood oxygen saturation) was measured in normoxia before (PRE) and after 15 nights (N15) hypoxia. Submaximal cycle ergometry was conducted PRE and after 4, 10, and 19 nights of hypoxia (N4, N10, and N19 respectively). Mean submaximal exercise V(E) was increased (P < 0.05) from PRE to N4 in LHTLc [74.4 (5.1) vs 80.0 (8.4) l min(-1); mean (SD)] and in LHTLi [69.0 (7.5) vs 76.9 (7.3) l min(-1)] and remained elevated in both groups thereafter, with no changes observed in CON at any time. Prior to LHTL, submaximal V(E) was not correlated with HVR, but this relationship was significant at N4 (r = 0.49, P = 0.03) and N19 (r = 0.77, P < 0.0001). Additionally, the increases in submaximal V(E) and HVR from PRE to N15-N19 were correlated (r = 0.51, P = 0.02) for the pooled data of LHTLc and LHTLi. These results suggest that enhanced hypoxic chemosensitivity contributes to increased exercise V(E) in normoxia following LHTL.
- Subjects
OXYGEN metabolism; ACCLIMATIZATION; ALTITUDES; COMPARATIVE studies; EXERCISE; RESEARCH methodology; MEDICAL cooperation; PHYSICAL fitness; RESEARCH; RESPIRATION; EVALUATION research; OXYGEN consumption
- Publication
European Journal of Applied Physiology, 2005, Vol 94, Issue 3, p207
- ISSN
1439-6319
- Publication type
journal article
- DOI
10.1007/s00421-004-1252-9