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- Title
Rosette-forming glioneuronal tumor - evidence of stem cell origin with biphenotypic differentiation.
- Authors
Chakraborti, S.; Mahadevan, A.; Govindan, A.; Bhateja, A.; Dwarakanath, S.; Aravinda, H.; Phalguni, A.; Santosh, V.; Yasha, T.; Rout, P.; Sampath, S.; Shankar, S.
- Abstract
Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a new addition to the WHO classification of central nervous system tumors. To date, 72 cases have been described in literature. In the present study, we report the clinical and imaging features, with detailed histopathological and immunohistochemical profile, of eight cases. Confocal microscopic evidence of stem cell origin with biphenotypic, glial and neurocytic differentiation is presented with a comprehensive review of literature.
- Subjects
STEM cells; CENTRAL nervous system tumors; IMMUNOHISTOCHEMISTRY; TUMORS; NEUROGLIA
- Publication
Virchows Archiv: European Journal of Pathology, 2012, Vol 461, Issue 5, p581
- ISSN
0945-6317
- Publication type
Article
- DOI
10.1007/s00428-012-1313-0